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Polynucleotides Under Eyes: Everything You Need To Know

Written by an Expert Aesthetic Content Writer Lisa.
Reviewed by Expert Medical Director Dr. Raj Thethi
Published on: January 17, 2025
Eye Care

polynucleotides under eyes

Have you heard that polynucleotides under the eyes are making waves in the beauty industry? Are you curious about the hype around this treatment? You are at the right place.

Polynucleotide treatment is an advanced skincare solution that brings the glow out of your skin by working at the cellular level.

Recently, polynucleotides used under the eyes have given better results than traditional methods. Explore the blog to learn everything about polynucleotides for under eyes.

Signs of Ageing Eyes 

The skin around the eyes is fragile and thinner. It also ages more rapidly than any other facial skin. This occurs because of:

  • Collagen and elastin decrease.
  • The muscles start weakening.

Sun rays, pollution, and stress increase the speed of ageing. All these cause a range of common concerns, such as:

  • Dark circles from pigmentation or shadowing.
  • Fine lines and wrinkles due to repeated facial expressions.
  • Puffy eyes from fluid retention or weakened muscles.
  • Sagging and hollows due to loss of volume or elasticity.

Polynucleotides: What Are They?

Polynucleotides are chains of nucleotides—the building blocks of DNA—typically derived from salmon. These biocompatible substances are like gentle nudges for your skin, promoting healing and cell regeneration and improving your skin’s appearance and health.

How Do Polynucleotides Work Under Your Eyes?

Wondering how do polynucleotides work? When injected into your under-eye skin, polynucleotides work by:

1. Collagen & Elastin Stimulation

Polynucleotides stimulate the synthesis of these essential proteins, making the skin firmer and more elastic.

2. Deep Hydration

They improve water retention in the skin, making it look plumper.

3. Anti-Infylammatory Properties

Polynucleotides soothe irritated skin, reducing redness and puffiness.

4. Skin Tone Improvement

They help to regulate pigmentation, brightening dark circles.

This treatment is becoming popular because it addresses the underlying causes of skin concerns rather than just masking them—the best you seek for ageing under eye skin.

Explore the guide ‘How to get rid of dark circles permanently?’ to explore natural and professional remedies for brighter eyes. 

Is Polynucleotide Good for Under Eyes?

Whether polynucleotides under the eyes are a “worth it” treatment depends on your skincare goals, budget, and what you want to address. 

Here’s a breakdown that may help you understand if it is worth it for you:

1. Natural Skin Revitalisation

Polynucleotides enhance your skin’s natural repair mechanisms rather than add artificial volume, thus giving you a more natural look by:

  • Reducing fine lines and wrinkles.
  • Brightening dark circles.
  • Hydrating under eye skin.
  • Improving skin texture and tone.
  • Strengthening skin barrier.

2. Multi-Benefits Approach

They address various concerns, such as hydration, fine lines, puffiness, and general skin texture. This makes them more versatile than treatments that target only one concern.

3.  Safe & Biocompatible

Polynucleotides are extracted from purified salmon DNA and are biocompatible with human skin, which means there is less chance of an adverse reaction and more chances of long-term skin health.

4. Long Lasting Benefits

Polynucleotide under eyes: How long does it last? It is not permanent, but you may enjoy the results for 6–9 months—longer than most topical treatments.

Considerations Before Getting Polynucleotides Under Your Eyes

Before getting polynucleotides under eye treatment, here are a few things you may consider. 

1. Results Appear Gradually.

If you’re seeking instant fixes, this treatment might not be for you. Polynucleotides take a few weeks to show visible improvements as the skin regenerates naturally.

2. Cost is a Factor.

Each session can cost between £300 and £600, and multiple sessions are often required. For those on a tight budget, the investment might feel steep.

3. There are a few Temporary Side Effects.

Mild swelling or redness at the injection site can occur but usually subsides in the first few days. To most, this is a small price to pay for the benefits.

Tear Trough Fillers vs Polynucleotides Under Eyes

polynucleotides or tear trough filler under your eyes

Tear trough fillers are injections made from hyaluronic acid. They fill in lost volume to help soften the appearance of hollowing under the eyes. Effects are instantaneous but short-term, usually 6–12 months.

On the other hand, polynucleotides concentrate on improving the quality of your under-eye skin. They help regenerate and repair the tissues, making them more effective in removing fine lines, pigmentation, and creepiness. They are long-lasting but natural.

When to Use Each Treatment

Tear Trough Fillers: Suitable for volume loss or hollowing.

Polynucleotides: Excellent for enhancing skin texture, hydration, and elasticity.

Combination: Some people do well with both. Polynucleotides correct the quality of skin, while fillers correct the structure.

Your practitioner will determine which is best suited to your needs.

Choosing Polynucleotides Under Eyes: Brighter & Healthier Skin

Polynucleotides are the next revolution in under-eye treatments. They act from the inside, giving you new skin through regeneration and repair, which translates into bright, firm, and healthy eyes.

The key is finding and consulting an expert practitioner for polynucleotides treatment in Leeds. They will understand your needs, skin goals, and whether this treatment suits you.

Together, you and the expert may craft your best approach to getting younger and vibrant eyre from here.

FAQs

1. How many sessions of polynucleotides are needed for under-eye?

For best results, you may need 2-3 sessions of polynucleotides under the eyes, 4 weeks apart.

2. Are polynucleotides better than fillers?

Polynucleotides stimulate fibroblasts and boost collagen at the cellular level. Unlike fillers, they enhance skin texture, minimise roughness, and improve hydration for lasting benefits. Your unique needs will determine the best choice.

3. How long do polynucleotides last under the eyes before and after?

Polynucleotide treatments help skin cell regeneration. Results appear after three months, with improvements lasting up to six months. Maintenance may only be needed every 3–4 months after that.

4. What are the risks of polynucleotides?

Polynucleotide treatments are safe, with minor risks of redness, swelling, bruising, or discomfort at the injection site, which resolves quickly. Infections or allergic reactions are rare.

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About Dr. Raj Thethi - Medical Reviewer

Dr. Raj Thethi

Yorkshire Skin Centre in Leeds is a CQC-registered medical clinic. It is led by Dr Raj Thethi who completed his core surgical training in hospitals around West Yorkshire before branching into aesthetics. Dr Raj Thethi is a Northern Territory Regional Expert for an international dermal filler company called Teoxane. He also sits on their National UK Faculty.

View all posts by Dr. Raj Thethi

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Blepharoplasty, also known as an eye lift, is a surgical procedure performed on the eyelids to improve their appearance. It can address concerns like:

  • Excess skin on the upper eyelids: This can obstruct vision and create a hooded appearance.

  • Bags under the lower eyelids: These can make you look tired or aged.

  • Drooping lower eyelids: This can also obstruct vision and contribute to a tired appearance.


Types of Blepharoplasty:

  • Upper blepharoplasty: This addresses concerns with the upper eyelids, removing excess skin and sometimes fat or muscle tissue.

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  • Asian blepharoplasty: This addresses specific concerns related to the anatomy of Asian eyelids, creating a more defined crease.