Disclaimer: This is educational content. It is not medical advice and should not replace guidance from your doctor or healthcare professional. Always speak to your healthcare provider before starting or changing any medication.
Ozempic is a medicine used to manage type 2 diabetes. It may cause side effects, just like medicines do. Some are mild, such as feeling sick, nausea, diarrhoea, or stomach discomfort, and often improve as your body gets used to it.
Other Ozempic side effects can be more serious and need medical attention.
In this guide, we explain the side effects you may notice, how to manage them, and when to see your doctor so you stay safe.
Ozempic contains a medicine called semaglutide. It works in several ways to help manage type 2 diabetes:
Because it works slowly in your body, Ozempic is injected once a week. This steady action helps your blood sugar stay more stable and can support gradual weight management.
Your doctor always prescribes the Ozempic dose for weight loss.
Many people taking Ozempic may notice mild side effects, especially when they first start or after increasing their dose. These are usually temporary and get better as your body adjusts.
Some common side effects include:
Feeling sick is common, especially at the start. It usually improves as your body gets used to the medicine.
Some people may vomit when their body is adjusting to Ozempic. Drinking fluids and eating bland foods can help.
Your bowel movements may become loose. Eating small meals and staying hydrated often eases this.
Some may find it hard to go to the toilet. Drinking more water and eating fibre can help keep things moving.
Mild stomach discomfort or gas is possible. Gentle movement and small meals may ease the discomfort.
You may feel burning in your chest or an upset stomach. Avoiding fatty or spicy foods can reduce this.
You might feel less hungry than usual. This usually improves over time as your body adjusts.
Feeling more tired than normal can happen in the first weeks. Rest and proper hydration often help.
The spot where you inject may be red, swollen, or sore. Changing injection sites each week can prevent irritation.
Most common side effects of Ozempic are mild and usually improve as your body adjusts. Here are some simple ways to manage them:
These mild side effects usually improve after a few weeks. If they persist or get worse, speak with your doctor.
While rare, some side effects need immediate attention. Here’s what to watch for:
Your gallbladder may become swollen or develop stones. Symptoms can include pain in the upper stomach, fever, yellowing of the skin or eyes, or clay-coloured stools. Contact your doctor if any of these appear.
Severe vomiting or diarrhoea can cause dehydration, which may harm your kidneys. Stay hydrated and speak to your doctor if you feel weak, dizzy, or notice reduced urine.
Some people may have swelling of the face, lips, tongue, or throat. Difficulty breathing or a severe rash can also occur. This is an emergency; call for help immediately.
This is more likely if you use Ozempic with insulin or other diabetes medicines. Symptoms include dizziness, sweating, hunger, confusion, or a fast heartbeat. Treat it quickly and tell your doctor.
The stomach may empty slowly, causing nausea, vomiting, bloating, and stomach pain. If you cannot keep food down or have severe bloating, contact your doctor.
Some people who take Ozempic experience a faster heartbeat. If you notice the same and it continues or is accompanied by dizziness or chest discomfort, speak to your doctor.
A few people may experience new or worsening anxiety, depression, or thoughts of self-harm. Contact your doctor on time if you notice any changes in mood or mental health.
Some effects of Ozempic may take longer to appear or last even after treatment, so it’s important to be aware of these potential long-term changes.
You may feel severe pain in your upper stomach that spreads to your back. Sometimes, this pain comes with vomiting or feeling very unwell. Pancreatitis requires urgent medical attention; contact your doctor immediately if you notice these symptoms.
If you already have eye problems from diabetes, they could get worse. Watch for blurred vision, sudden changes in sight, or eye pain. See an eye specialist or doctor right away.
“Ozempic face” happens when you lose fat quickly from your face. This can make cheeks look sunken, skin appear looser, or give a gaunt appearance. Over time, your skin may adjust, but some people notice changes in how their face looks after significant weight loss.
Rapid weight loss can also affect the shape of your bottom also called “ozempic Butt“. Some people notice a reduction in volume, making the butt appear smaller or less rounded. Maintaining muscle through exercise can help reduce this effect.
“Ozempic feet” happens when fat and muscle are lost from the feet. They may look wrinkled, saggy, or slimmer than before. Usually, the skin slowly adjusts, but it can take time to regain a more natural appearance.
This is very rare, but it can happen. Look out for a lump or swelling in your neck, difficulty swallowing, a hoarse voice, or shortness of breath. If you notice any of these, see a doctor straight away.
While most people tolerate Ozempic well, you must take precautions to lower the risk of serious or long-term side effects. Here’s what you can do:
Take Ozempic on the same day each week. Don’t increase your dose too quickly; let your body adjust.
Tell your doctor about all medicines, supplements, or vitamins you take. Discuss any history of thyroid problems, pancreatitis, kidney issues, or gallbladder disease.
Make it your routine to check your blood sugar; also, get your kidney and eye checks done as advised. Report any new lumps, swelling, or unusual symptoms early.
Drink enough water daily, especially if you have nausea, vomiting, or diarrhoea. Dehydration can worsen kidney problems or digestive issues.
Try eating in smaller portions slowly. Do not eat foods that are rich in fats, fried, or very sugary, as they can upset your stomach.
Inform all healthcare professionals before any procedure. Ozempic slows digestion, which can affect anaesthesia or surgery.
Avoid Ozempic if pregnant, planning pregnancy, or breastfeeding unless your doctor approves.
It is wise not to ignore any symptoms like severe stomach pain, vision changes, swelling, or allergic reactions.
Remember: Early reporting can prevent complications.
Here’s what you may expect from Ozemoic side effects:
Who should not take Ozempic: People with type 1 diabetes, a history of thyroid cancer (MTC), Multiple Endocrine Neoplasia type 2 (MEN 2), or severe allergies to semaglutide should avoid it.
Pregnancy & breastfeeding: Ozempic is not recommended if you are pregnant, planning pregnancy, or breastfeeding. Always speak to your doctor first.
Before surgery or anaesthesia: Tell your doctor or surgeon if you take Ozempic. It slows digestion, which may affect procedures under anaesthesia.
Reporting medications: Always tell your doctor about all medicines, supplements, or vitamins you take. This helps prevent low blood sugar if Ozempic is combined with other diabetes drugs.
Some side effects are mild and go away on their own, but you should contact your doctor if you notice anything serious or unusual.
See a doctor immediately if you experience:
Also, contact your doctor if:
Always err on the side of caution; your doctor can help adjust your treatment or provide advice to keep you safe.
Many people report that they only experienced mild side effects, such as nausea, diarrhoea, or mild stomach discomfort, which usually improve as the body adjusts.
Serious side effects are seen in rare cases, but it’s important to know what to watch for and to contact your doctor if anything concerning arises.
For a safer and more comfortable treatment journey, you must follow your prescribed dose, stay hydrated, eat small meals, and keep your doctor informed about any other medications or health conditions. All of it reduces the risks of complications.
If you are considering starting Ozempic or want guidance on managing side effects, Yorkshire Skin Centre in Leeds can provide expert advice and support to ensure safe and effective treatment.
Yes. Appetite returns after stopping, so some weight regain is common. Healthy eating and exercise can help.
Mild effects include nausea, vomiting, diarrhoea, constipation, or stomach upset. Rarely, serious issues like pancreatitis, gallbladder problems, low blood sugar, eye problems, kidney injury, or severe allergic reactions can happen.
You can’t know for sure. Rapid weight loss or changes in the face, like sunken cheeks or more wrinkles (“Ozempic face”), can be a clue. Stomach upset may also occur.
Rapid weight loss can make your face look sunken or loose. Skin may adjust over time, but changes can be noticeable.
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Consultant Plastic Surgeon
Dr. Mark Gorman is a consultant plastic surgeon and department lead at Salford Royal, specialising in facial plastics and complex reconstructive procedures. His expertise spans a wide range of areas, including oculoplastic, nasal, ear, abdominal, and microsurgical reconstruction, with particular focus on breast, head and neck, and lower limb reconstruction.
With a non-surgical and surgical skillet, Dr. Gorman is known for using advanced techniques to achieve natural, harmonious results. His approach often integrates dermal fillers and fat transfer to enhance facial features in combination with a range of deep plane facelifts.
Beyond facial aesthetics, his specialties include high-definition liposuction, allowing for precise body contouring.
Dr. Gorman’s approach to plastic surgery is rooted in skill, combining technical precision with a deep understanding of aesthetics to achieve refined and personalised outcomes for each patient.Dr.Gorman is a key opinion leader (KOL) for major UK aesthetic companies, also has taught at BAAPS (British Association of Aesthetic Plastic Surgeons), bringing his expertise to the next generation of surgeons.
Additionally, he runs his own aesthetic training company, further extending his influence in the field.Dedicated to total well-being, Dr. Gorman created the Look Body Mind philosophy, which blends aesthetics and wellness for a holistic approach to beauty.Whether you’re looking for subtle enhancements or comprehensive reconstructive work, Dr. Gorman’s patient-centered care, grounded in precision, skill and an exceptional aesthetic eye, ensures that you will feel confident throughout your journey.
Administrator
Sophie brings over a decade of customer service expertise to her role as Receptionist at Yorkshire Skin Centre. With a strong foundation in retail management and the travel industry, she is recognised for her warm, approachable manner and professional attitude—ensuring every client feels welcomed and valued from the moment they arrive.
Highly organised and calm under pressure, Sophie thrives in fast-paced environments and seamlessly manages a wide range of front-of-house responsibilities.
As the first point of contact for many clients, she plays a vital role in maintaining the clinic’s high standards of service and creating a smooth, reassuring experience for all visitors.
Beyond her professional skills, Sophie brings a vibrant energy to the team. She has a passion for travel, fashion, and music, and is currently learning both Spanish and Arabic. Her dedication to personal growth, combined with her friendly and proactive approach, makes her an indispensable part of our team.
Senior Surgical Sister(RN)
Herezel McCourt is a highly experienced Registered Nurse at Yorkshire Skin Centre, bringing over two decades of clinical expertise across diverse surgical and medical specialties. She holds a BSc (Hons) in Perioperative Practice from Huddersfield University, UK, and a BSc in Nursing from Cebu Doctors’ University in the Philippines.
Herezel has spent the majority of her career within the NHS, most recently as a Clinical Specialist in Ophthalmic Surgery at The MidYorkshire Teaching NHS Trust.
Her extensive background includes roles in operating theatres, anaesthetic care, ENT, urology, plastics, maxillofacial, orthopaedic, and podiatric nursing, among others.
Renowned for her professionalism, dedication, and compassionate care, Herezel is also a trained mentor, assessor, and ANTT trainer. She has led initiatives in recruitment, risk assessment, SOP development, and patient care pathway planning. Her leadership credentials are strengthened by a Level 3 Award in First Line Management and a strong commitment to staff development and peer support.
Herezel is a calm and supportive presence to both patients and colleagues, and her attention to clinical excellence makes her an invaluable member of the Yorkshire Skin Centre team.
Clinical Assistant
Rhea Levitt is a highly experienced Clinical Assistant at Yorkshire Skin Centre, known for her hands-on approach, warm personality, and commitment to delivering high-quality patient care. With a solid background in healthcare settings, Rhea brings valuable clinical expertise and administrative support to the team.
Her wide-ranging experience includes phlebotomy, wound care, ECGs, diabetic foot checks, B12 injections, and assisting in minor surgical procedures. She is also skilled in patient health monitoring, spirometry, and providing support during clinics such as coil fittings and cancer care.
Rhea’s well-rounded clinical knowledge is matched by her excellent organisational skills and a calm, compassionate approach to patient wellbeing.
In addition to her clinical duties, Rhea supports the practice by carrying out internal audits and ensuring best practices are upheld throughout the clinic. She plays a key role in maintaining smooth day-to-day operations and upholding the high standards that Yorkshire Skin Centre is known for.
Dedicated, professional, and always ready to help, Rhea is an invaluable member of the team who helps ensure that every patient receives attentive, safe, and seamless care.
Administrator
Raman holds a Bachelor of Science with Bachelor of Education (BSc, BEd) from India, a qualification that integrates scientific studies and teaching education, equipping her with a strong foundation in both fields. She is currently building her career in the UK healthcare industry, bringing her hardworking, compassionate, and friendly nature to the team.
With valuable experience in customer service and patient care, Raman plays a key role in managing day-to-day operations, handling bookings, and ensuring a smooth and welcoming experience for all patients.
Her dedication to excellence and passion for healthcare and client well-being make her an integral part of our team.
Practitioner
Nichola is a highly skilled practitioner with a strong background in beauty and holistic therapies. She earned her Level 3 Beauty Therapy qualification with distinction from the Yorkshire College of Beauty and further enhanced her expertise with Level 4 Specialist training. She is also CIDESCO-certified, an internationally recognized gold standard in beauty and spa therapy, ensuring clients receive the highest level of care and treatments.
With 18 years of customer service experience, primarily in the hospitality industry, Nichola deeply understands the importance of building strong client relationships. She is known for her hardworking nature, punctuality, and dedication to continuous learning.
Passionate about skincare and wellness, Nichola is committed to expanding her expertise in a leading skin clinic. She believes that the knowledge and experience she gains will be invaluable in delivering the highest standard of care to her clients.
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Founder and Medical Director
Dr Raj is the Founder and Clinical Director of the Yorkshire Aesthetic Clinic. With a successful career in aesthetics and a passion for patient care, Dr. Raj found that his expertise in facial aesthetics was a natural progression where he could showcase his warm and friendly demeanour alongside his exceptional skills.
Dr Raj specialises in advanced facial aesthetics, offering a wide range of treatments and skin procedures. With his extensive training and experience in both medical and aesthetic fields, he brings a unique perspective to delivering exceptional results.
Driven by his passion for patient satisfaction, Dr Raj established the Yorkshire Aesthetic Clinic. Located in a comfortable and welcoming environment, the clinic provides a luxurious and refined setting for patients seeking aesthetic treatments…. Read More
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Patient Representative
Hi, I’m Sarah Coates. I’m a Senior Change Manager, Hogan accredited coach, proud mum of 2 beautiful boys and am blessed with incredible friends to get into mischief with!
As I headed towards my 40th birthday, my life changed in a way that I could never have imagined and I came off that roller coaster with a new lease of life, with an understanding of the importance of self care and a huge amount of gratitude.
I love to travel, have a passion for interior design and enjoy sharing all that life has to offer with my beautiful family and fabulous friends.
If I’m not at work, you’ll find me playing at the park with my boys, enjoying the sun in Ibiza, listening to music or at the bar with a glass of fizz!
Patient Representative
Patient Representative
I am Senior Manager currently working for a small charity based in Leeds. My role is both professionally stimulating and challenging. No two days are ever the same. It includes aspects of advocacy, client rights, individual representation and inclusivity.
One milestone that resonates deeply is the creation of support groups, safe spaces where clients can openly share their stories. Witnessing the impact of these connections has fuelled my determination to improve the journey of others.
Through my own aesthetic endeavours , I’ve developed an unparalleled understanding of the emotional nuances tied to cosmetic treatments. This empathy allows me to offer sincere reassurance and guidance, especially during moments of vulnerability, in an era of aesthetic care that marries technical expertise with genuine human understanding and a person centred approach.
In my spare time I love the outdoors, enjoying hillwalking, taking part in sport, managing my bountiful allotment, and enhancing my cookery skills trying different cuisines (..no Masterchef yet).. and travel.
Consultant and General Surgeon
Dr. Khan earned her MD from Copenhagen University in 2003 and boasts over 20 years of medical expertise. Her early career was dedicated to dermatology and gynaecology across Yorkshire, and in 2011, she became a qualified GP from The Royal College of General Practitioners in London.
Dr. Khan’s commitment to women’s health is evident through her achievements. In 2012, she earned a Diploma in Sexual and Reproductive Health.
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Expert Practitioner
Yorkshire Skin Centre in Leeds is a CQC registered medical clinic. Led by Dr Raj Thethi who completed his core surgical training in hospitals around West Yorkshire before branching into aesthetic medicine.
Dr Raj Thethi is a Northern Territory Regional Expert for an international dermal filler company called Teoxane. He also sits on their National UK Faculty. He is nationally recognised leader in the field of Aesthetics and a skilled trainer up..Yorkshire Skin Centre in Leeds is a CQC registered medical clinic. Led by Dr Raj Thethi who completed his core surgical training in hospitals around West Yorkshire before branching into aesthetic medicine.
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Consultant Ophthalmologist & Oculoplastic Surgeon
Mr Jeeva is celebrated for his mastery in aesthetic eyelid surgery. By adopting a patient-centric ethos, he delivers personalised treatments that amplify natural beauty and revive youthful vitality.
He has completed a prestigious fellowship at the Royal College of Surgeons, specialising in cosmetic plastic surgery. This rigorous training has endowed him with advanced techniques in aesthetic surgery, ensuring outcomes that are both beautiful and natural.
With a specialised fellowship in oculoplastic surgery, Mr Jeeva has honed his skills in delicate eyelid surgeries, tear duct disorders… Read More
Independent Nurse Prescriber
Alana embarked on a career in nursing in 2008, following her comprehensive training and graduation. Since then, she has accrued a wealth of experience working in a variety of roles within both the NHS and private healthcare sectors. Known for her dedication and exceptional skills, Alana rapidly ascended into management, and for the past seven years, has been serving as a matron.
Throughout her career, she has consistently maintained her clinical competencies and academic studies. She initially earned a Bachelor’s degree in Nursing, later advancing her studies to become an Advanced Nurse Practitioner and Independent Prescriber. Her commitment to continuous professional development led to the completion of her full Master’s degree.
Alana’s passion for skin spurred her to further specialise in this field. In 2017, she pursued training in facial aesthetics, a decision that marked the beginning of a significant new chapter in her career. Since then, she has been affiliated with several leading skin clinics across the UK, where she has honed her expertise and built a reputation for excellence. Her extensive knowledge and experience in skin led her to become an expert medical trainer and since 2021, Alana has been imparting her knowledge at an award-winning training academy. Previously, she held the prestigious position of National Trainer for SKN Clinics, where she educated a variety of medical professionals, including plastic surgeons.
While Alana enjoys all aspects of skin, she has a particular fondness for medical-grade skin care, which she believes offers unparalleled benefits to patients. Her dedication to patient care and her professional knowledge and skills, make her a standout figure in this field. Through her work, Alana has positively impacted numerous lives, helping patients achieve their best skin health and aesthetic goals. In her trainer role, Alana is known for her meticulous approach and her ability to convey complex information in an accessible manner, ensuring that her trainees are well-equipped to deliver high-quality care. Her leadership and mentorship have been crucial in elevating the standards of practice within the industry.
Alana’s career is a testament to her unwavering commitment to excellence in nursing and aesthetics. Her professional journey reflects a blend of clinical expertise, academic achievement, and a genuine passion for improving patient care. As she continues to advance her career, Alana remains dedicated to staying at the forefront of the field, continually enhancing her skills and knowledge to provide the best possible care to her patients and to train the next generation of skin care professionals.
Consultant Plastic & Reconstructive Surgeon
With over 15 years of experience in the NHS, Mr Nikos Lymperopoulos specialises in reconstructive and cosmetic plastic surgery. He graduated from the University of Athens Medical in 2009 and completed his basic surgical training in Liverpool. After earning a PhD with honours in DIEP clinical anatomy research in 2013, he completed advanced surgical training in plastic surgery across Yorkshire and Liverpool, including a cosmetic fellowship in the North West.
Mr Lymperopoulos further honed his expertise with two prestigious breast reconstruction microsurgical fellowships at The Royal Marsden Hospital in Chelsea and Guy’s & St Thomas’ Hospitals in London. His extensive experience in breast reconstruction after mastectomy provides a profound understanding of surgical anatomy and aesthetics, benefiting procedures such as breast augmentation, reduction, and uplift. Additionally, he is highly skilled in abdominoplasty, often enhanced with liposuction or muscle repair, especially post-pregnancy.
Specialising in skin cancer treatment, he adeptly handles Basal Cell Carcinoma, Squamous Cell Carcinoma, and Melanoma. He offers a comprehensive range of breast and body cosmetic surgeries, including breast augmentation with implants or fat transfer, breast reduction, uplift, tummy tucks, and liposuction. Combined procedures, such as “mommy makeovers,” are also available to restore post-pregnancy body contours.
Trained in both surgical and non-surgical facial rejuvenation, Mr Lymperopoulos performs eyelid surgery (blepharoplasty), as well as toxin and filler injections. Currently, he serves as a Consultant at Mid Yorkshire Teaching Hospitals, specialising in breast reconstruction and skin cancer surgery, and holds an Honorary Senior Lecturer position at the University of Leeds.
An advocate for education and research, Mr Lymperopoulos has over 20 publications in peer-reviewed journals and a PhD in microsurgical breast reconstruction. As an Education Lead, he developed “The Yorkshire FRCS (Plast) Course” to aid UK trainees in their exit exams. His innovative training simulator was awarded first place in Innovation at the BAPRAS meeting in 2021.
Blepharoplasty, also known as an eye lift, is a surgical procedure performed on the eyelids to improve their appearance. It can address concerns like:
Excess skin on the upper eyelids: This can obstruct vision and create a hooded appearance.
Bags under the lower eyelids: These can make you look tired or aged.
Drooping lower eyelids: This can also obstruct vision and contribute to a tired appearance.
Types of Blepharoplasty:
Upper blepharoplasty: This addresses concerns with the upper eyelids, removing excess skin and sometimes fat or muscle tissue.
Lower blepharoplasty: This addresses concerns with the lower eyelids, removing excess fat or skin and sometimes repositioning tissues.
Asian blepharoplasty: This addresses specific concerns related to the anatomy of Asian eyelids, creating a more defined crease.
