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Profhilo Gone Wrong: Potential Side Effects & What To Do

Written by an Expert Aesthetic Content Writer Lisa.
Reviewed by Expert Medical Director Dr. Raj Thethi
Published on: May 5, 2025
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Profhilo

Profhilo gone wrong

Profhilo is now a top skin treatment for giving tired, ageing skin an instant pick-me-up, but in some cases. It achieves this through the use of hyaluronic acid to hydrate and enhance the firmness of the skin deeply— no filler, no extra volume, just that natural glow.

Although the vast majority of people only suffer mild side effects (or none at all), some have had more concerning experiences, making it a Profhilo gone wrong case. 

If you’re considering getting Profhilo, or you’ve already received it and something doesn’t seem right, then this blog is for you.

We’ll guide you through the side effects, how to remain safe, and what to do if something goes wrong.

Can Profhilo Go Wrong?

One of the most common questions individuals ask is: “Is Profhilo safe, and can it go wrong?”

The answer is: Yes, Profhilo is generally considered safe, but like any aesthetic treatment, there is a small risk of complications. These cases are rare, and most issues can be avoided by choosing an experienced and qualified practitioner.

Let’s now understand the signs and symptoms that may indicate something has gone wrong with Profhilo.

Side Effects of Profhilo Treatment

Most people leave their Profhilo treatment with radiant skin and no issues. But it’s always good to understand what side effects can occur– even if they’re unlikely. Here are the signs & symptoms of Profhilo gone wrong.

1. Unusual Redness

A small redness at injection sites is absolutely normal. It can last a few minutes up to a few hours. 

If redness spreads, becomes hot to the touch, or lasts more than 2–3 days, it may be a sign of infection or inflammation and you should speak to your practitioner or GP.

2. Swelling that Doesn’t Improve

Puffiness is to be expected, particularly in the areas of the cheeks or around the eyes. It is just your body reacting to the injection and the product itself.

If swelling looks unusual, feels firm, grows larger, or doesn’t improve within 72 hours, it could be a sign of a reaction or incorrect placement – seek medical advice.

3. Extreme Bruising

A common side effect, especially if you’re prone to bruising or take blood-thinning medication like aspirin.

If bruising is very dark, spreads quickly, or becomes painful and swollen, it may be linked to a deeper issue and should be checked by a professional.

4. Tenderness

Your skin might feel sore or sensitive where the needles went in. This should ease quickly and is usually mild.

If the area becomes increasingly painful or the skin feels hot, it could be a sign of infection or tissue irritation— don’t ignore it.

5. Persistent Swelling or Lumps

Although temporary and occasional bumps are normal, if you experience hard lumps that persist for weeks or return swelling, it may be an indication of a more serious problem. These may occur because of:

  • Improper injection depth
  • A poor technique
  • An allergic reaction to the product
  • Localised swelling or fluid accumulation

It might not hurt, but if the area feels odd, lumpy, or doesn’t settle after a week, have it checked.

6. Allergic Reaction

Although Profhilo contains hyaluronic acid – a naturally occurring substance in the skin – allergic reactions can still occur, particularly because of stabilisers in the product. You may get:

  • Severe itching or burning
  • Red, raised rashes or hives
  • Swelling, particularly around the eyes or lips
  • Difficulty breathing or tight chest (this is very rare but serious – call 999 immediately)

If you’ve ever had a reaction to dermal fillers or skincare products, tell your practitioner beforehand.

7. Blocked Blood Vessel

Vascular occlusion is one of the most dangerous dangers of any injectable treatment. If Profhilo is injected into a blood vessel or very close to one by mistake, it can occlude the blood supply. The skin in the area may not receive enough oxygen, which can lead to damage.

Symptoms may include:

  • Sudden, sharp pain in the treated area
  • Skin that becomes white, dusky, grey, or purple
  • Cool or cold areas of skin
  • Blisters or skin texture change

If it occurs, it’s a medical emergency and should be treated promptly to avoid damage to the skin or scarring. Go straight to A&E or contact your practitioner immediately.

8. Infection

Despite being unlikely if good hygiene is practiced, there is still a chance an infection can develop if the injected area is touched repeatedly after or gets exposed to germs. Some signs of infection are:

  • Increased redness instead of a disappearance.
  • Heat and tenderness in the injection site.
  • Pus or yellow discharge oozing from the skin.
  • Feeling sick or having a fever.

An infection can generally be treated with antibiotics, but the trick is to get it early.

Knowing how long does Profhilo last may help you decide if it’s suitable for you.

What To Do If Your Profhilo Has Gone Wrong?

If you feel that something has gone wrong following your Profhilo treatment, do the following:

1. Contact Your Practitioner Immediately

Let them know what’s happened and how you feel. A reputable clinic will help you and recommend the next course of action.

2. Take Photos

This will record changes in your skin and be helpful for medical advice and treatment follow-up.

3. Don’t Touch or Press the Area

You may be tempted to rub lumps or massage tender areas – don’t. It can worsen or spread infection.

4. Go to Your General Physician If Needed

If there is a lot of pain, unusual skin colour, swelling that does not decrease, or infection signs – visit a doctor or go to A&E immediately.

5. Obtain a Second Opinion

If your initial practitioner is not cooperative, talk to another professional. You are entitled to proper treatment.

What Leads to Profhilo Gone Wrong?

Most side effects can be prevented by taking a few easy precautions. Here’s how to stay safe:

Choose the Right Practitioner

  • Visit someone properly trained in Profhilo and other injectable procedures.
  • Don’t be tempted by cheap prices – skill is more important than price.
  • Request to view before-and-after photos of their work.

Ask the Right Questions

You may ask these questions to your doctor:

  • How regularly do you conduct Profhilo treatments?
  • What do I do if there’s a complication?
  • What do I need to do after the appointment?

A good practitioner will always be pleased to explain.

Follow Aftercare Instructions Carefully

What you do afterwards is also important:

  • Avoid rubbing or touching the treated skin.
  • Skip alcohol, the gym, and hot showers for 24–48 hours.
  • Don’t wear make-up on treatment day.
  • Avoid direct sun exposure and saunas.

Monitor Your Skin

If things don’t look or feel normal, don’t wait for them to sort themselves out. Always seek advice – it’s safer to err on the side of caution.

Have a Patch Test

If you have extremely sensitive skin or allergies, discuss a patch test with your practitioner beforehand.

Final Thoughts

Profhilo treatment in Leeds is an excellent treatment in the right hands – it can give your skin a hydration and glow boost. But no cosmetic treatment is 100% risk-free.

Having knowledge of potential side effects, going to a qualified practitioner, and listening to your body are the best ways to be safe.

And if something doesn’t feel right, trust your instincts and get the help you need.

FAQs

1. Can anything go wrong with Profhilo?

Yes, things can go wrong, but it’s rare. You might get lumps, swelling, or a reaction if it’s not done properly.

2. Does Profhilo leave lumps?

It can leave small lumps at first, but they usually go away in a day or two. If they stay longer, see your practitioner.

3. Is Profhilo really worth it?

Many people say yes – it gives skin a natural glow and feels refreshed. Just make sure you go to a trusted professional.

4. What is the alternative to Profhilo?

Alternatives include skin boosters like Seventy Hyal or dermal fillers. Your practitioner can help choose what’s best for you.

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About Dr. Raj Thethi - Medical Reviewer

Dr. Raj Thethi

Yorkshire Skin Centre in Leeds is a CQC-registered medical clinic. It is led by Dr Raj Thethi who completed his core surgical training in hospitals around West Yorkshire before branching into aesthetics. Dr Raj Thethi is a Northern Territory Regional Expert for an international dermal filler company called Teoxane. He also sits on their National UK Faculty.

View all posts by Dr. Raj Thethi

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