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Ozempic Face: How to Avoid it?

Written by an Expert Aesthetic Content Writer Lisa.
Reviewed by Expert Medical Director Dr. Raj Thethi
Published on: July 10, 2025
Face

Ozempic Face

Many people are talking about the weight loss effects of Ozempic. As Ozempic gains popularity for treating diabetes and losing weight, some people are observing surprising changes. Their faces appear thinner, older, or more hollow than before. This change is being referred to as “Ozempic face”.

But is it the medication that is causing the Ozempic face, or is it merely a side effect of quick weight loss? Can you prevent it, and if not, is it treatable?

This blog explains everything you need to know. We will cover what causes Ozempic face, what it looks like, how it affects your appearance, and your options for prevention & treatment. You’ll also learn about the risks, benefits & side effects of Ozempic, so you can make informed choices about your health. Let’s get started.

What is Ozempic and How Does It Work?

Ozempic

Ozempic is a medicine that is prescribed to control blood sugar levels in people with type 2 diabetes. It contains semaglutide and is taken as a weekly injection.

Ozempic is categorised as a GLP-1 receptor agonist, a category of medication that replicates a hormone naturally produced in the body that is involved in managing blood sugar levels. Here’s what it does:

  • Helps your body release more insulin after meals, which reduces blood sugar.
  • Reduces the hormone glucagon, which otherwise raises blood sugar.
  • Slows down digestion, which makes you feel full for longer and possibly helps reduce food intake.

Ozempic is used to treat type 2 diabetes, and many individuals also experience weight loss as a result of its use. This weight loss happens because the medication reduces appetite and slows digestion, which can naturally lead to eating less.

However, Ozempic isn’t suitable for everyone. It’s not recommended for individuals who have a personal or family history of certain thyroid cancers or for those allergic to semaglutide. Always get medical advice before taking a new medication.

What is Ozempic Face?

“Ozempic face” refers to the changes in a person’s facial appearance that may occur when they lose weight rapidly, particularly when using medications such as Ozempic. These changes might include a thinner or more hollow-looking face, sagging skin, deeper lines or wrinkles, and a tired or older appearance overall.

It’s important to understand that these changes aren’t caused directly by the medicine itself. They’re more about what happens when you lose a lot of weight in a short time. Your body fat decreases, including the natural fat that gives your face shape and fullness. As that fat disappears, the skin can look looser or more aged.

The term started gaining attention on social media, especially when people began noticing how rapid weight loss affected facial features. But it’s not an official medical diagnosis. This change can happen not just with Ozempic, but also with other medications, surgery, or extreme dieting.

Symptoms and Signs of Ozempic Face

Here are some common facial changes you might start to notice.

  • Sunken cheeks & eyes: When someone loses fat in their face, it can lead to a hollow or sunken appearance in the cheeks and areas around the eyes.
  • Sagging or loose skin: Rapid weight loss can leave skin looking less taut, especially around the jawline, neck, or chin.
  • Increased wrinkles and fine lines: Less facial fat and reduced collagen can make wrinkles more prominent, giving an aged appearance.
  • Thin lips: Fat loss can reduce the plumpness of lips, which makes them appear thinner.
  • Hollowed-out appearance: The overall look can be described as gaunt, tired, or older than before.
  • Dark circles under the eyes: Rapid weight loss can highlight dark circles, making the under-eye area look more shadowed or tired.
  • Overall aged appearance: The combination of fat loss and skin changes can make the face look significantly older than before starting Ozempic.
  • Changes in facial proportions: The loss of fat can alter the balance of facial features, making some areas (like the nose or chin) appear more prominent.

Causes of Ozempic Face

The main cause of Ozempic face is rapid weight loss. Here’s why this happens:

  • Loss of Facial Fat: Your face naturally has fat pads, especially in the cheeks, temples, and under the eyes, that give it a youthful, full appearance. When you lose weight quickly, these fat pads shrink, leading to a hollow or sunken look.
  • Skin Elasticity: As you lose weight, your skin may not shrink at the same rate as the underlying tissue. This is especially true for older adults or those who lose a lot of weight, as skin elasticity decreases with age or prolonged stretching. Rapid weight loss doesn’t give the skin time to adjust, resulting in sagging.
  • Collagen and Elastin Loss: Losing weight can lead to a decrease in collagen and elastin, which are proteins that help keep skin firm and elastic. This can worsen wrinkles and sagging, making facial changes more noticeable.
  • Dehydration: Ozempic can cause side effects like nausea, vomiting, or diarrhoea, which may lead to dehydration. Dehydrated skin can look more wrinkled and less plump, amplifying the effects of an Ozempic face.
  • Age and Pre-existing Fat: Older adults or those with more facial fat before starting Ozempic may notice more pronounced changes. Faster and more significant weight loss is likely to cause these effects.

How Can Ozempic Affect the Face?

Ozempic lowers blood sugar and curbs appetite, which often leads to noticeable weight loss. While this can be a good thing for overall health, losing weight too quickly can cause some unwanted changes in appearance. This is especially true when weight loss occurs from the face.

Your face naturally holds fat that gives it shape and keeps the skin smooth and firm. When that fat disappears quickly, it can lead to loose skin, wrinkles, and a more hollow or aged look. The skin may also struggle to bounce back because of lower levels of collagen and elastin, which help keep it tight and elastic.

Side Effects of Ozempic (Beyond Ozempic Face)

While Ozempic face is a cosmetic concern, Ozempic has other side effects, some of which are more serious. 

Common side effects include:

  • Gastrointestinal Issues: Nausea, vomiting, diarrhoea, constipation, and stomach pain are the most common, which affects many people, especially when starting the medicine or increasing the dose. These usually lessen over time.
  • Low Blood Sugar (Hypoglycemia): This is more likely when Ozempic is used with other diabetes medications like insulin or sulfonylureas. Symptoms include dizziness, shakiness, confusion, and sweating.
  • Dehydration: Vomiting and diarrhoea can lead to dehydration, which may cause kidney problems or worsen skin changes.

Rare but serious side effects include:

  • Pancreatitis: Pancreatitis can trigger intense pain in the abdomen, along with symptoms like nausea & vomiting. This requires immediate medical attention.
  • Gallbladder Problems: Ozempic may increase the risk of gallstones or gallbladder inflammation, with symptoms like upper abdominal pain or jaundice.
  • Thyroid Tumours: Ozempic might increase the risk of thyroid tumors, including a rare cancer called medullary thyroid carcinoma (MTC). While it’s unclear if this risk applies to humans, those with a history of thyroid cancer should avoid Ozempic.
  • Kidney Problems: Dehydration or pre-existing kidney issues can increase the risk of acute kidney injury.
  • Allergic Reactions: Rare but serious reactions like swelling or difficulty breathing require emergency care.
  • Gastroparesis and Intestinal Blockage: Ozempic may increase the risk of stomach paralysis or intestinal blockage, both of which can be serious.
  • Vision Changes: Some people report worsening vision, particularly if they have diabetic retinopathy.
  • Pregnancy: Ozempic is not a safe option during pregnancy. You should stop using it at least two months before trying to conceive.
  • Breastfeeding: We don’t yet know if Ozempic passes into breast milk. Discuss with your doctor whether it’s safe to continue your medication if you are breastfeeding.

Benefits of Ozempic

Despite the side effects, Ozempic offers significant benefits, particularly for those with type 2 diabetes or weight-related health issues. These include:

  • Improved Blood Sugar Control: Ozempic works by helping your body release insulin when your blood sugar is high and by lowering the hormone that raises blood sugar. This helps bring down average blood sugar levels (HbA1c), especially in people with type 2 diabetes.
  • Weight Loss: Many people lose significant weight, which can improve conditions like high blood pressure, high cholesterol, and obesity-related health risks.
  • Cardiovascular Benefits: Ozempic reduces the risk of heart attack, stroke, or death in people with type 2 diabetes and heart disease.
  • Kidney Protection: It helps to slow the progress of chronic kidney disease and lowers the chances of kidney failure or cardiovascular-related death.
  • Improved Metabolic Health: Beyond weight loss, Ozempic can improve insulin sensitivity and reduce metabolic complications.

Risks of Using Ozempic for Weight Loss

Using Ozempic solely for weight loss, especially without a medical need, comes with risks:

  • Shortages for Diabetes Patients: The surge in off-label use has caused shortages, making it harder for those with type 2 diabetes to access the medication.
  • Weight Regain: Stopping Ozempic can lead to weight regain, increased cravings, and blood sugar spikes, which can reverse health benefits.
  • Disordered Eating: The focus on rapid weight loss can contribute to unhealthy attitudes toward food and body image, potentially leading to eating disorders.
  • Serious Side Effects: As mentioned, risks like pancreatitis, gallbladder issues, and thyroid tumours require careful monitoring.
  • Cosmetic Concerns: Beyond Ozempic face, people may experience sagging skin in other areas, like the buttocks or breasts, which can be distressing.

If weight loss is your goal, talk to your doctor about FDA-approved weight loss medications like Wegovy, which is a higher dose of semaglutide specifically designed for weight management.

How to Avoid Ozempic Face? – Treatment Options

Non-Surgical Treatments for Ozempic Face

There are several non-surgical options that can help improve the appearance of Ozempic face. These treatments work by restoring lost facial volume and tightening the skin, which can make the face look more refreshed and youthful.

1. FaceTite

FaceTite is a non-surgical option that addresses the Ozempic face. This method uses radiofrequency energy for fat reduction and skin firming. It targets the deeper layers of the skin without cutting or stitches. 

This treatment is great for people who have mild to moderate sagging in the face or neck and want visible tightening without going through surgery. It can also help define the jawline and reduce jowls caused by rapid weight loss.

2. Dermal Fillers

Fillers are injected into specific areas of the face to replace volume that’s been lost due to rapid weight loss. They can help fill out hollow cheeks, smooth wrinkles, and lift sagging skin. 

Some fillers also encourage your body to produce more collagen over time, which helps improve skin structure naturally. You can typically see results immediately, and they often last for several months.

3. Radiofrequency Microneedling

Radiofrequency microneedling enhances skin elasticity and collagen production through the combined action of heat energy and microscopic needles. It helps tighten loose skin, improve texture, and make the face look firmer. It’s especially useful for people dealing with sagging or thin skin after quick weight loss. One well-known version of this treatment is called Morpheus8, which targets deeper layers of the skin for more noticeable results.

4. Nitrogen Plasma Treatments

Nitrogen plasma addresses the entire skin layer using controlled heat. This process helps in skin healing and boosts the production of collagen and elastin, which in turn can lead to a reduction in wrinkles and firmer skin. This treatment is a good option for people looking for skin rejuvenation without surgery.

Surgical Treatments for Ozempic Face

In more severe cases where non-surgical options aren’t enough, surgery may be considered. These procedures are designed to restore lost volume, tighten skin, and reshape the face for a more youthful appearance.

1. Facelift

A facelift is a surgical method used to lift and firm the underlying facial structures, helping to restore a more youthful contour. It can improve sagging, restore volume, and give a more defined look to the cheeks and jawline. There are different types of facelifts depending on how much correction is needed, from small adjustments to more extensive reshaping.

2. Fat Transfer to the Face

A fat transfer procedure involves removing fat from one area of your body, such as the stomach or thighs, and then injecting it into facial regions that have experienced volume loss. It’s a natural way to restore fullness and smooth out facial features. Since it uses fat from your own body, the results usually appear more natural and subtle.

3. Neck Lift

Losing weight quickly can leave loose skin around the neck and jaw. A neck lift can address this by tightening the area and removing extra skin, giving the jawline a more defined and toned appearance.

4. Eyelid Surgery (Blepharoplasty)

Weight loss can sometimes make your eyes appear hollow or fatigued. Eyelid surgery can address this by removing excess skin and fat from the eye area.

Upper blepharoplasty targets excess skin and fat on the upper eyelids. This can help open up the eyes, reduce drooping, and create a more refreshed look.

Lower blepharoplasty, on the other hand, focuses on puffiness, under-eye bags, and sagging skin beneath the eyes. It smooths out the lower eye area and reduces that sunken or shadowed appearance.

How to Fix Ozempic Face Naturally?

If your face looks tired, sunken, or older after using Ozempic, it’s likely due to fast weight loss. But there are simple, natural ways to help your face recover over time.

1. Lose weight slowly: Rapid weight loss leads to more facial volume loss. Try to aim for a gradual and steady pace to give your skin time to adjust.

2. Stay hydrated: Enough water consumption keeps your skin supple and plump. Make it a goal to stay hydrated by drinking about eight glasses of water each day.

3. Eat enough protein: Protein helps your skin and muscles stay strong. Foods like eggs, chicken, tofu, or lentils are great sources.

4. Add healthy fats to your diet: Omega-3 fats from foods like salmon, walnuts, and avocados support skin moisture and firmness.

5. Eat fruits and vegetables daily: These give your body the vitamins and antioxidants it needs to keep skin healthy and glowing.

6. Moisturise your face regularly: A good moisturiser keeps your skin hydrated and can reduce the appearance of sagging.

7. Use retinoids or hyaluronic acid: These skincare ingredients help improve skin texture and boost firmness over time.

8. Wear sunscreen daily: Sunscreen is crucial for skin protection, as sun exposure can intensify wrinkles and lead to more sagging. Even if the weather is cloudy, use sunscreen every day.

9. Exercise consistently: Regular movement, especially strength training, helps improve blood flow and muscle tone in your face.

10. Reduce stress: Long-term stress accelerates the skin’s ageing process. Make time to relax, whether that’s getting enough sleep, spending time outdoors, or doing something that makes you feel good.

Final Thoughts

Ozempic face is mostly a side effect of rapid weight loss, not the medication itself. As facial fat disappears quickly, it can leave your face looking older or more hollow. But fortunately, it’s not permanent. You can improve it naturally with slower weight loss, proper hydration, good nutrition, and skincare. 

To address lost volume or skin laxity, both non-surgical and surgical interventions are available if needed. The key is to stay informed, pay attention to how your body responds, and take a balanced approach to your health and appearance throughout the weight loss process.

Frequently Asked Questions

1. What does Ozempic do to your face?

Ozempic may cause quick weight loss, which could result in facial fat reduction. This can make the skin look looser, the face look more hollow, and wrinkles more noticeable.

2. Can Ozempic cause a sunken face?

Yes, it can. Some people notice sunken eyes, more hollow cheeks, and changes in the size or shape of their lips, chin, and face overall.

3. Can Ozempic face be fixed?

In many cases, yes. You can improve it through skincare, diet, exercise, and if needed, medical treatments that restore facial volume or tighten skin.

4. Is Ozempic safe to use long term?

It can be, but long-term use may increase the risk of serious side effects like gallbladder problems or digestive issues. It’s important to stay in touch with your doctor while using it.

5. Can exercise help with the Ozempic face?

Yes. Strength training helps build and maintain muscle, which can reduce the sunken look and support the skin during weight loss.

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About Dr. Raj Thethi - Medical Reviewer

Dr. Raj Thethi

Yorkshire Skin Centre in Leeds is a CQC-registered medical clinic. It is led by Dr Raj Thethi who completed his core surgical training in hospitals around West Yorkshire before branching into aesthetics. Dr Raj Thethi is a Northern Territory Regional Expert for an international dermal filler company called Teoxane. He also sits on their National UK Faculty.

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Blepharoplasty

Blepharoplasty, also known as an eye lift, is a surgical procedure performed on the eyelids to improve their appearance. It can address concerns like:

  • Excess skin on the upper eyelids: This can obstruct vision and create a hooded appearance.

  • Bags under the lower eyelids: These can make you look tired or aged.

  • Drooping lower eyelids: This can also obstruct vision and contribute to a tired appearance.


Types of Blepharoplasty:

  • Upper blepharoplasty: This addresses concerns with the upper eyelids, removing excess skin and sometimes fat or muscle tissue.

  • Lower blepharoplasty: This addresses concerns with the lower eyelids, removing excess fat or skin and sometimes repositioning tissues.

  • Asian blepharoplasty: This addresses specific concerns related to the anatomy of Asian eyelids, creating a more defined crease.